A TALE OF TWO
COUNTRIES |
|
BY KARI LARSEN
|
For more than a decade the
United States and Australia have been two of the most conspicuous holdouts
against signing the 1997 Kyoto Protocol on greenhouse gas reduction. The conservative administrations
that led both countries during much of this period initially professed skepticism about global
warming claims, and expressed distress regarding China’s and India’s lack of emissions caps. In addition,
both countries depend upon coal for much of their energy needs and thus have significant economic
concerns over the cost of capping carbon emissions. |
BIOFUEL GENOME MAPPED |
|
BY LUCAS ARGUESO, PH.D.![]() Dr. Argueso, who is from the Duke Department of Molecular Genetics and Microbiology, worked with researchers from Brazil and the University of North Carolina on the study: Margaret Dominska and John H. McCusker, of the Duke Department of Molecular Genetics and Microbiology; Fred S. Dietrich, also of the Department of Molecular Genetics and Microbiology and the Duke Institute for Genome Sciences and Policy; Piotr A. Mieczkowski, of the Department of Genetics at the University of North Carolina, Chapel Hill and Brazilian scientists from Campinas State University; and the University of São Paulo. |
DURHAM, NC - A strain of yeast that thrives on turning
sugar cane and other tough grasses into ethanol that might be used as
biofuel has had its genome completely sequenced. This yeast strain studied
and mapped is known as PE-2. Understanding this microbe may enable more
efficient biofuel production and will produce even more robust industrial
organisms that are versatile and capable of producing advanced biofuels
from non-food crops like switchgrass. I worked with researchers from Brazil and the University of North Carolina on the study. Now we have sequenced the genome, so we have a road map that will allow us to build upon its natural abilities. This opens the door to crossing yeast strains to make even more efficient yeasts for enhanced biofuel production. |
The PE-2 genome will aid research into finding the best and strongest yeasts for converting the cellulose in grasses into biofuel.
I believe this strain has a natural talent for carbohydrate biofuels that have not yet been introduced in the United States. When the technology is engineered to effectively break down cellulose, I believe this strain of yeast will be an ideal delivery vehicle for that technology.
The study also yielded some interesting genetic information
about Saccharomyces cerevisiae, the most studied and utilized yeast species.
The study was funded by two grants from the National Institutes of Health,
a BRASKEM/FAPESP grant, and support from ETH Bioenergia, a Brazilian company
that produces ethanol and sugar from sugar cane.
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